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DTSTART;TZID=America/Los_Angeles:20261201T150000
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UID:500-1796137200-1796144400@systems.bio.uci.edu
SUMMARY:Cedric Feschotte\, PhD- Systems Biology Seminar Series
DESCRIPTION:Systems Biology Seminar Series\n\n\n\nTuesday\, December 1st\, 2026 at 3:00pm\n\n\n\nThis seminar will be In-Person.\n\n\n\n\n\n\n\n\n\n\n\n\n\nCedric Feschotte\, PhD\n\n\n\nBarbara McClintock Professor\, Molecular Biology and Genetics\, Cornell University\, Ithaca\, NY\n\n\n\n \n\n\n\n\n\n\n\n\nMobile and Mandatory: Active Transposons as Essential Genes \n\n\n\nAbstract:Transposable elements (TEs; or transposons) make up the bulk of eukaryotic genomes and have a profound impact on the biology and evolution of species. Notably\, TE sequences are a recurrent source of genetic material coopted to assemble new genes\, control gene expression\, and fuel evolutionary novelty. However\, in nearly all cases of TE cooption\, only parts of individual TE sequences are repurposed for cellular function and generally coopted TEs have long ceased to transpose. By contrast\, actively mobile TEs are typically viewed as strictly selfish: they are thought to confer no immediate benefit to their host\, and their replicative activities threaten genome integrity. In this talk\, I will challenge this dogma by presenting evidence that active TE families in zebrafish and in human provide activities essential for the development and physiology of their host organism. \n\n\n\nBio: \n\n\n\n\nCornell Faculty Profile\n\n\n\nThe Feschotte Lab
URL:https://systems.bio.uci.edu/event/cedric-feschotte-phd-systems-biology-seminar-series/
LOCATION:4201 Natural Sciences II\, 4201 Natural Sciences II\, Irvine\, California\, 92697\, United States
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