Welcome to the Department of Systems Biology at UC Irvine

Leading the way to Discovery, Explanation, and Prediction

Department of Systems Biology

The Department of Systems Biology is dedicated to understanding the complexity of living systems through the integration of quantitative, computational, and experimental approaches. Our faculty and researchers work at the forefront of interdisciplinary science, bridging mathematics, physics, engineering, computer science, and the biological sciences to uncover the principles that govern biological processes at multiple scales, from molecules and cells to tissues and organisms.

Fluorescence Microscope image of Bovine Pulmonary Artery Endothelial Cells BPAE stained for mitochondria, phalloidin, and nuclei undergoing mitosis

Research at Systems Biology

The Department of Systems Biology is home to a diverse and dynamic portfolio of research programs that span the intersection of biology, mathematics, physics, engineering, and data science. Our faculty lead cutting-edge investigations into gene-regulatory networks, cell signaling and communication, tissue patterning and morphogenesis, stem cell dynamics, and the quantitative modeling of evolutionary and disease processes. By leveraging advanced genomic and computational tools, single-cell technologies, multi-omics approaches, and mathematical modeling, our research programs are designed to decode the complex and emergent behaviors of biological systems across multiple scales. Collaborative by design, our programs unite experimentalists and theorists to tackle fundamental questions in development, cancer biology, immunology, evolution, and neuroscience, driving discoveries that have lasting impact on both basic science and human health. Through innovative research and rigorous training, the department prepares the next generation of scientists to address fundamental questions in health, disease, and development. We are committed to fostering a collaborative and inclusive environment where discovery thrives and scientific boundaries are pushed forward.

Scroll to Top